
Katherine Heigl became one of the biggest rom-com stars of the 2000s while also making her name as a dramatic actress in popular TV series. With her charismatic presence, sharp humor and dramatic depth, she has built a versatile career. Here are her 10 best films and series.
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Grey's Anatomy (2005-2010): The Role That Made Her a Star
As Dr. Izzie Stevens, a talented but emotionally complex doctor, Heigl became world-famous in Grey's Anatomy. Her character balanced humor, romance and heartbreaking drama, and her storyline with Denny Duquette (Jeffrey Dean Morgan) is among the show's most tragic. She won an Emmy for the role.
Knocked Up (2007): The Rom-Com That Made Her a Superstar
In this hilarious, relatable comedy, Heigl plays Alison Scott, an ambitious TV journalist who unexpectedly gets pregnant after a one-night stand with a slacker (Seth Rogen). The film was a huge success and made her one of the most in-demand actresses in the genre.
The film was a huge success and made her one of the most in-demand actresses in the genre.
27 Dresses (2008): The Ultimate Wedding Rom-Com
As Jane, the eternal bridesmaid who's always there for others but never finds love herself, Heigl played a classic feel-good role. Her chemistry with James Marsden and her perfect timing made it a favorite among rom-com fans.
One of the best ever imo.
The Ugly Truth (2009): A Spicy Clash With Gerard Butler
In this cheeky, sarcastic rom-com, Heigl plays Abby Richter, a romantic TV producer forced to work with a crude macho dating expert (Gerard Butler). Their comic battle and fiery chemistry made it one of the spiciest rom-coms of her career.
The dialogue is so endlessly quotable. (2)
Life as We Know It (2010): Romance and Drama After Tragedy
Heigl plays Holly, a woman who shares custody of a baby with a man (Josh Duhamel) after the death of their mutual friends. It combines heartbreaking drama with humor and romance.
Firefly Lane (2021-2023): Friendship Across Decades
In this Netflix series, Heigl plays Tully Hart, a successful but troubled talk show host whose lifelong friendship with Kate (Sarah Chalke) is at the center. Her layered acting shows she's still a powerful dramatic actress.
Killers (2010): Action and Romance With a Wink
In this action rom-com, Heigl plays Jen, a woman who discovers her husband (Ashton Kutcher) is actually a former secret agent. A mix of romance and spy action in which Heigl holds her own.
One for the Money (2012): Crime Comedy With a Tough Twist
As Stephanie Plum, an unemployed woman who reluctantly becomes a bounty hunter, Heigl plays a sharp, brave and funny lead in this book adaptation, showing her talent for action and snappy humor.
Unforgettable (2017): Psychological Thriller With a Dark Edge
In this tense thriller, Heigl plays Tessa Connover, an ex-wife who becomes obsessed with her ex-husband's new fiancée. With an intense, manipulative and ice-cold performance, she proved she could shine as a thriller villain.
Suits (2018-2019): A Strong Legal Comeback
In the later seasons of Suits, Heigl played Samantha Wheeler, a tough, smart lawyer who joins the firm. A strong, confident role showing she fits perfectly in high-stakes drama.
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Izzie Stevens, a talented but emotionally complex doctor, Heigl became world-famous in Grey's Anatomy.